Interface prototype · Not a live product. Fixed goldenset data. The backend is still in development.

Follow a finding.

Explore one ingredient, its observations, and the source paper.

INGREDIENT PROFILE / CURATED EXAMPLE

Lactobionic acid

INCI: LACTOBIONIC ACID · Abbreviation: LA

4 selected human observations from one goldenset paper

GOLDENSET #2 · SKIN BARRIERDirect

Skin surface pH decreased one hour after application.

Human study · 10% w/w formulation · Significant decrease

Inspect evidence & source

Comparison: Lower pH versus placebo-treated and untreated sites, as recorded in the manual goldenset.

Context: A 10% lactobionic acid formulation in an alkyl polyglucoside (APG) emulsion. The placebo was the same emulsion without lactobionic acid.

Interpretation: This is a pH outcome. It does not establish a molecular mechanism or a general benefit for every formulation.

Manual goldenset #2 · Paraphrased observation, not a verbatim quote.

View source paper →
GOLDENSET #3 · SKIN BARRIERDirect

No significant change in transepidermal water loss after 24-hour occlusion.

Human study · 10% w/w formulation · No significant change

Inspect evidence & source

Outcome: TEWL (transepidermal water loss) did not change significantly after 24-hour occluded application.

Interpretation: “No significant change” is kept as its own outcome. It is not a demonstrated decrease in water loss or proof of equivalence.

Manual goldenset #3 · Paraphrased observation, not a verbatim quote.

View source paper →
GOLDENSET #1 · MOISTURIZINGDirect

Stratum corneum hydration increased after 24-hour occlusion.

Human study · 10% w/w formulation · Significant increase

Inspect evidence & source

Comparison: The increase in stratum corneum hydration (SCH) was also significant versus placebo.

Context: This observation concerns hydration under the reported study conditions, separate from the paper’s pH and water-loss measurements.

Manual goldenset #1 · Paraphrased observation, not a verbatim quote.

View source paper →
GOLDENSET #4 · SOOTHING CATEGORYDirect

No significant change in erythema index after 24-hour occlusion.

Human study · 10% w/w formulation · No significant change

Inspect evidence & source

Outcome: Erythema index, a measure of skin redness, showed no significant change in this observation.

Interpretation: The goldenset assigns this to the soothing category as an adverse-effect observation. It is not evidence that redness decreased, or a guarantee of no irritation in other conditions.

Manual goldenset #4 · Paraphrased observation, not a verbatim quote.

View source paper →

QUESTION → EVIDENCE / SCRIPTED PREVIEW

Start with a question.

These are written examples, not generated answers or live search results.

PREWRITTEN EXAMPLE

Two observations, two different outcomes.

In the manual goldenset, skin surface pH decreased after one hour, while TEWL showed no significant change after 24-hour occlusion. Both are human observations for a 10% w/w formulation. They measure different outcomes and should be read separately.

Inspect skin barrier observations →

The planned product would retrieve evidence for a question and preserve the study context. This prototype only switches between fixed, manually written examples.

SOURCE PAPER / GOLDENSET 01

A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation — An in vivo/in vitro study

Tasić-Kostov, Lukić & Savić · Journal of Cosmetic Dermatology · 2019

DOI: 10.1111/jocd.12908

What is represented here

The prototype displays four selected human observations from the repository’s manual goldenset. It does not reproduce the full paper or all of its observations.

  • Skin surface pH: significant decrease at one hour.
  • TEWL: no significant change after 24-hour occlusion.
  • Stratum corneum hydration: significant increase after 24-hour occlusion, including versus placebo.
  • Erythema index: no significant change after 24-hour occlusion.

What stays separate

The goldenset also contains in vitro observations and claims attributed to earlier studies. Those are not pooled with these human results. No molecular target is assigned to this paper in the goldenset.

Return to observations

Curated research example · Not formulation or treatment advice. Questions about the project? founder@ciontic.com ↗